# Matching Primary Tumor and Blood Gene Expression Analysis of HPV-negative Squamous Head and Neck Cancers

> **NCT07512921** · — · RECRUITING · sponsor: **Fondazione IRCCS Istituto Nazionale dei Tumori, Milano** · enrollment: 300 (estimated)

## Conditions studied

- Head and Neck (HNSCC)

## Interventions

- **OTHER:** Standard of Care (Investigator Choice)

## Key facts

- **NCT ID:** NCT07512921
- **Lead sponsor:** Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2025-02-18
- **Primary completion:** 2027-07-31
- **Final completion:** 2027-12-31
- **Target enrollment:** 300 (ESTIMATED)
- **Last updated:** 2026-04-06

## Collaborators

- Azienda Ospedaliero Universitaria di Sassari
- Istituto Nazionale Tumori IRCCS - Fondazione G. Pascale
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
- Pineta Grande Hospital, Castel Volturno (CE), Italy
- Istituto Europeo di Oncologia
- San Raffaele University Hospital, Italy

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07512921

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07512921, "Matching Primary Tumor and Blood Gene Expression Analysis of HPV-negative Squamous Head and Neck Cancers". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT07512921. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*