# Omission of Postoperative Radiation in HPV-Associated Oropharyngeal Cancer Using ctHPVDNA Surveillance (OPERATION)

> **NCT07513389** · PHASE2 · NOT_YET_RECRUITING · sponsor: **Medical University of South Carolina** · enrollment: 36 (estimated)

## Conditions studied

- Squamous Cell Carcinoma
- Human Papilloma Virus (HPV)
- Oropharyngeal Squamous Cell Carcinoma (OPSCC)

## Interventions

- **OTHER:** Active Surveillance With ctHPVDNA (NavDx®)

## Key facts

- **NCT ID:** NCT07513389
- **Lead sponsor:** Medical University of South Carolina
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-07-01
- **Primary completion:** 2029-07-01
- **Final completion:** 2030-07-01
- **Target enrollment:** 36 (ESTIMATED)
- **Last updated:** 2026-04-07


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07513389

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07513389, "Omission of Postoperative Radiation in HPV-Associated Oropharyngeal Cancer Using ctHPVDNA Surveillance (OPERATION)". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT07513389. Licensed CC0.

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