# The Feasibility and Safety of RK-4 Injection Bypassing Blood-brain Barrier in the Treatment of Acute Large Hemispheric Infarction Using Intracalvariosseous Injection Device

> **NCT07514949** · NA · NOT_YET_RECRUITING · sponsor: **yilong Wang** · enrollment: 6 (estimated)

## Conditions studied

- Stroke
- Acute Ischemic Stroke
- Blood-Brain Barrier

## Interventions

- **DEVICE:** RK-4 ICO injection
- **OTHER:** Conventional treatment

## Key facts

- **NCT ID:** NCT07514949
- **Lead sponsor:** yilong Wang
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-04-15
- **Primary completion:** 2026-11-15
- **Final completion:** 2026-11-15
- **Target enrollment:** 6 (ESTIMATED)
- **Last updated:** 2026-04-07


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07514949

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07514949, "The Feasibility and Safety of RK-4 Injection Bypassing Blood-brain Barrier in the Treatment of Acute Large Hemispheric Infarction Using Intracalvariosseous Injection Device". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT07514949. Licensed CC0.

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