# ASCEND-1: Lifestyle Intervention Plus Mazdutide for Weight Management

> **NCT07517042** · NA · RECRUITING · sponsor: **Shanghai Zhongshan Hospital** · enrollment: 420 (estimated)

## Conditions studied

- Obesity
- Weight Control

## Interventions

- **DRUG:** Mazdutide
- **BEHAVIORAL:** Intensive Lifestyle Intervention

## Key facts

- **NCT ID:** NCT07517042
- **Lead sponsor:** Shanghai Zhongshan Hospital
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-04
- **Primary completion:** 2028-12
- **Final completion:** 2028-12
- **Target enrollment:** 420 (ESTIMATED)
- **Last updated:** 2026-04-08


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07517042

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07517042, "ASCEND-1: Lifestyle Intervention Plus Mazdutide for Weight Management". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT07517042. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
