# Dextromethorphan-Bupropion on Striatal Activity in Adults With Major Depressive Disorder

> **NCT07523048** · PHASE2 · RECRUITING · sponsor: **Roger McIntyre** · enrollment: 30 (estimated)

## Conditions studied

- Major Depressive Disorder (MDD)

## Interventions

- **DRUG:** Dextromethorphan-Bupropion

## Key facts

- **NCT ID:** NCT07523048
- **Lead sponsor:** Roger McIntyre
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-11-21
- **Primary completion:** 2026-07
- **Final completion:** 2027-01
- **Target enrollment:** 30 (ESTIMATED)
- **Last updated:** 2026-04-13

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07523048

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07523048, "Dextromethorphan-Bupropion on Striatal Activity in Adults With Major Depressive Disorder". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT07523048. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*