# Microbiota trAnSplant ThERaPy In hEpatiC Encephalopathy (MASTERPIECE)

> **NCT07528690** · PHASE2 · NOT_YET_RECRUITING · sponsor: **VA Office of Research and Development** · enrollment: 162 (estimated)

## Conditions studied

- Hepatic Encephalopathy
- Cirrhosis

## Interventions

- **BIOLOGICAL:** Microbiota transplant therapy (MTT) capsules
- **OTHER:** Placebo capsule

## Key facts

- **NCT ID:** NCT07528690
- **Lead sponsor:** VA Office of Research and Development
- **Sponsor class:** FED
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-10-30
- **Primary completion:** 2030-10-31
- **Final completion:** 2031-03-03
- **Target enrollment:** 162 (ESTIMATED)
- **Last updated:** 2026-04-14


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07528690

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07528690, "Microbiota trAnSplant ThERaPy In hEpatiC Encephalopathy (MASTERPIECE)". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT07528690. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*