# Proton-Based Total Marrow Irradiation for Allogeneic Transplantation in High-Risk AML/MDS

> **NCT07532824** · PHASE1,PHASE2 · RECRUITING · sponsor: **Institute of Hematology and Blood Transfusion, Czech Republic** · enrollment: 16 (estimated)

## Conditions studied

- Acute Myeloid Leukemia (AML)
- Myelodysplastic Syndrome (MDS)/AML
- Proton Therapy
- MDS and AML Prior to Allogeneic SCT
- Myelodysplastic Neoplasm

## Interventions

- **RADIATION:** Proton Total Marrow Irradiation

## Key facts

- **NCT ID:** NCT07532824
- **Lead sponsor:** Institute of Hematology and Blood Transfusion, Czech Republic
- **Sponsor class:** OTHER
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-11-21
- **Primary completion:** 2029-11
- **Final completion:** 2029-11
- **Target enrollment:** 16 (ESTIMATED)
- **Last updated:** 2026-04-16

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07532824

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07532824, "Proton-Based Total Marrow Irradiation for Allogeneic Transplantation in High-Risk AML/MDS". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT07532824. Licensed CC0.

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