# The Investigators Will Evaluate the Diagnostic Performance of [18F]-AlF-FAPI-74 PET/CT in Inflammatory Disorders and Compare it With the Current Gold Standard for Inflammation, FDG PET/CT, in Three Patient Cohort: Patients Presenting With Fever of Unknown Origin, IgG4-RD and AxSpA.

> **NCT07535554** · PHASE2,PHASE3 · RECRUITING · sponsor: **Universitaire Ziekenhuizen KU Leuven** · enrollment: 140 (estimated)

## Conditions studied

- Fever of Unknown Origin
- IgG4 Related Disease
- Axial Spondylarthritis (axSpA)
- Inflammation of Unknown Origin

## Interventions

- **DIAGNOSTIC_TEST:** [18F]AlF-FAPI-74 PET/CT

## Key facts

- **NCT ID:** NCT07535554
- **Lead sponsor:** Universitaire Ziekenhuizen KU Leuven
- **Sponsor class:** OTHER
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-09-17
- **Primary completion:** 2029-03-31
- **Final completion:** 2030-03-31
- **Target enrollment:** 140 (ESTIMATED)
- **Last updated:** 2026-04-17


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07535554

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07535554, "The Investigators Will Evaluate the Diagnostic Performance of [18F]-AlF-FAPI-74 PET/CT in Inflammatory Disorders and Compare it With the Current Gold Standard for Inflammation, FDG PET/CT, in Three Patient Cohort: Patients Presenting With Fever of Unknown Origin, IgG4-RD and AxSpA.". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT07535554. Licensed CC0.

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