# Comparative Efficacy of Once-daily LAMA/LABA Combinations Versus Tiotropium on Constant-work-rate Cycle Endurance in COPD

> **NCT07541378** · NA · SUSPENDED · sponsor: **Medical University of Bialystok** · enrollment: 100 (estimated)

## Conditions studied

- COPD (Chronic Obstructive Pulmonary Disease)

## Interventions

- **DRUG:** Tiotropium
- **DRUG:** Olodaterol
- **DRUG:** Umeclidinium
- **DRUG:** Vilanterol
- **DRUG:** Indacaterol
- **DRUG:** Glycopyrronium

## Key facts

- **NCT ID:** NCT07541378
- **Lead sponsor:** Medical University of Bialystok
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** SUSPENDED
- **Start date:** 2024-03-11
- **Primary completion:** 2025-02-07
- **Final completion:** 2027-09-01
- **Target enrollment:** 100 (ESTIMATED)
- **Why stopped:** Recruitment was temporarily suspended pending additional funding and activation of additional study centers. The pilot phase has been completed and is currently being evaluated. The suspension was not related to safety concerns.
- **Last updated:** 2026-04-21


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07541378

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07541378, "Comparative Efficacy of Once-daily LAMA/LABA Combinations Versus Tiotropium on Constant-work-rate Cycle Endurance in COPD". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT07541378. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*