# Therapeutics for Moderate and Severe Dengue

> **NCT07543458** · PHASE3 · NOT_YET_RECRUITING · sponsor: **Oxford University Clinical Research Unit, Vietnam** · enrollment: 8800 (estimated)

## Conditions studied

- Dengue
- Severe Dengue
- Mosquito-Borne Diseases
- Vector Borne Diseases
- Arbovirus Infections
- Flavivirus Infections
- RNA Virus Infections
- Hemorrhagic Fever

## Interventions

- **DRUG:** Placebo
- **DRUG:** Dexamethasone
- **DRUG:** N-Acetylcysteine
- **OTHER:** Standard of care
- **DRUG:** Baricitinib

## Key facts

- **NCT ID:** NCT07543458
- **Lead sponsor:** Oxford University Clinical Research Unit, Vietnam
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-10-01
- **Primary completion:** 2030-07-31
- **Final completion:** 2031-07-31
- **Target enrollment:** 8800 (ESTIMATED)
- **Last updated:** 2026-04-21

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07543458

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07543458, "Therapeutics for Moderate and Severe Dengue". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT07543458. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*