# Superior Mesenteric Artery First Versus Standard Approach in Pancreaticoduodenectomy

> **NCT07547033** · NA · NOT_YET_RECRUITING · sponsor: **Assistance Publique - Hôpitaux de Paris** · enrollment: 150 (estimated)

## Conditions studied

- Pancreatic Adenocarcinoma
- Pancreatic Head Cancer

## Interventions

- **PROCEDURE:** SMA-first pancreaticoduodenectomy using either right posterior or anterior approach. SMA identified and isolated with peri-adventitial dissection before any irreversible section.
- **PROCEDURE:** Conventional pancreaticoduodenectomy without prior isolation of the SMA; antero-posterior approach of the uncinate process after pancreatic section.

## Key facts

- **NCT ID:** NCT07547033
- **Lead sponsor:** Assistance Publique - Hôpitaux de Paris
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-09-01
- **Primary completion:** 2030-09-01
- **Final completion:** 2031-09-01
- **Target enrollment:** 150 (ESTIMATED)
- **Last updated:** 2026-04-23


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07547033

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07547033, "Superior Mesenteric Artery First Versus Standard Approach in Pancreaticoduodenectomy". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT07547033. Licensed CC0.

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