# Suzetrigine for Treatment and Reduction of Intense Discomfort After knEe Replacement PAIN

> **NCT07548385** · PHASE3 · RECRUITING · sponsor: **Icahn School of Medicine at Mount Sinai** · enrollment: 235 (estimated)

## Conditions studied

- Total Knee Replacement Surgery
- Post-operative Pain

## Interventions

- **DRUG:** Suzetrigine
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT07548385
- **Lead sponsor:** Icahn School of Medicine at Mount Sinai
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-04
- **Primary completion:** 2027-02-23
- **Final completion:** 2027-02-23
- **Target enrollment:** 235 (ESTIMATED)
- **Last updated:** 2026-04-23


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07548385

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07548385, "Suzetrigine for Treatment and Reduction of Intense Discomfort After knEe Replacement PAIN". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT07548385. Licensed CC0.

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