# ALTO-207 in Adults With Treatment-resistant Depression (TRD)

> **NCT07553637** · PHASE2 · RECRUITING · sponsor: **Alto Neuroscience** · enrollment: 178 (estimated)

## Conditions studied

- Treatment-resistant Depression (TRD)

## Interventions

- **DRUG:** ALTO-207
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT07553637
- **Lead sponsor:** Alto Neuroscience
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-05
- **Primary completion:** 2027-11
- **Final completion:** 2027-12
- **Target enrollment:** 178 (ESTIMATED)
- **Last updated:** 2026-04-28


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07553637

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07553637, "ALTO-207 in Adults With Treatment-resistant Depression (TRD)". Retrieved via AI Analytics 2026-07-19 from https://api.ai-analytics.org/clinical/NCT07553637. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*