# The ARISE Trial Compares Whether Giving Routine Steroid Replacement or Using Targeted Blood Tests to Guide Replacement Better Protects Certain Patients From Adrenal Insufficiency After the Removal of a Diseased Adrenal Gland.

> **NCT07558135** · NA · NOT_YET_RECRUITING · sponsor: **King's College Hospital NHS Trust** · enrollment: 96 (estimated)

## Conditions studied

- Adrenal Gland Disease

## Interventions

- **DRUG:** Empirical Hydrocortisone Protocol
- **DRUG:** Targeted Treatment Protocol

## Key facts

- **NCT ID:** NCT07558135
- **Lead sponsor:** King's College Hospital NHS Trust
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-09
- **Primary completion:** 2028-09
- **Final completion:** 2028-12
- **Target enrollment:** 96 (ESTIMATED)
- **Last updated:** 2026-04-30


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07558135

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07558135, "The ARISE Trial Compares Whether Giving Routine Steroid Replacement or Using Targeted Blood Tests to Guide Replacement Better Protects Certain Patients From Adrenal Insufficiency After the Removal of a Diseased Adrenal Gland.". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT07558135. Licensed CC0.

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