# MOTIF@FRESH: Modifying Organisms Transvaginally in Females @ FRESH

> **NCT07566754** · PHASE2 · NOT_YET_RECRUITING · sponsor: **Douglas Kwon** · enrollment: 75 (estimated)

## Conditions studied

- Recurrent Bacterial Vaginosis (BV)

## Interventions

- **BIOLOGICAL:** Vaginal Microbiome Transplantation (VMT)
- **DRUG:** oral metronidazole
- **OTHER:** Sterile saline solution

## Key facts

- **NCT ID:** NCT07566754
- **Lead sponsor:** Douglas Kwon
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-09
- **Primary completion:** 2027-05
- **Final completion:** 2028-02
- **Target enrollment:** 75 (ESTIMATED)
- **Last updated:** 2026-05-05

## Collaborators

- Massachusetts General Hospital
- Bill and Melinda Gates Foundation

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07566754

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07566754, "MOTIF@FRESH: Modifying Organisms Transvaginally in Females @ FRESH". Retrieved via AI Analytics 2026-06-05 from https://api.ai-analytics.org/clinical/NCT07566754. Licensed CC0.

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