# Tracking and Predicting How Brain Damage Spreads in Neurodegenerative Diseases

> **NCT07567664** · NA · ENROLLING_BY_INVITATION · sponsor: **IRCCS San Raffaele** · enrollment: 645 (estimated)

## Conditions studied

- Neurodegenerative Disease
- Behavioral Variant Frontotemporal Dementia (bvFTD)
- Primary Progressive Aphasia(PPA)
- Progressive Supranuclear Palsy(PSP)
- Amyotrophic Lateral Sclerosis (ALS)
- Cortical Basal Syndrome (CBS)

## Interventions

- **DIAGNOSTIC_TEST:** 3 Tesla MRI without contrast medium
- **GENETIC:** Blood sample for genetic analysis
- **DIAGNOSTIC_TEST:** Cerebrospinal fluid sampling (CSF)
- **DIAGNOSTIC_TEST:** Neurological evaluation
- **DIAGNOSTIC_TEST:** Neuropsychological evaluation

## Key facts

- **NCT ID:** NCT07567664
- **Lead sponsor:** IRCCS San Raffaele
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** ENROLLING_BY_INVITATION
- **Start date:** 2017-06-01
- **Primary completion:** 2027-02-15
- **Final completion:** 2027-03-01
- **Target enrollment:** 645 (ESTIMATED)
- **Last updated:** 2026-05-05

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07567664

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07567664, "Tracking and Predicting How Brain Damage Spreads in Neurodegenerative Diseases". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT07567664. Licensed CC0.

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