# Proof of Principle Study for an Efficacy Trial of Linaclotide for Cystic Fibrosis

> **NCT07569419** · EARLY_PHASE1 · RECRUITING · sponsor: **University of Nottingham** · enrollment: 26 (estimated)

## Conditions studied

- Cystic Fibrosis (CF)

## Interventions

- **DRUG:** Linaclotide 290 micrograms
- **DRUG:** Lactose placebo pill

## Key facts

- **NCT ID:** NCT07569419
- **Lead sponsor:** University of Nottingham
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-03-09
- **Primary completion:** 2026-08
- **Final completion:** 2026-10
- **Target enrollment:** 26 (ESTIMATED)
- **Last updated:** 2026-05-06


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07569419

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07569419, "Proof of Principle Study for an Efficacy Trial of Linaclotide for Cystic Fibrosis". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT07569419. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*