# AMAZE 4: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea

> **NCT07571109** · PHASE3 · NOT_YET_RECRUITING · sponsor: **Novo Nordisk A/S** · enrollment: 300 (estimated)

## Conditions studied

- Obesity
- Overweight
- Obstructive Sleep Apnoea

## Interventions

- **DRUG:** NNC0487-0111
- **DRUG:** Placebo (matched to NNC0487-0111)

## Key facts

- **NCT ID:** NCT07571109
- **Lead sponsor:** Novo Nordisk A/S
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-05-05
- **Primary completion:** 2028-06-26
- **Final completion:** 2028-07-24
- **Target enrollment:** 300 (ESTIMATED)
- **Last updated:** 2026-05-06


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07571109

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07571109, "AMAZE 4: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT07571109. Licensed CC0.

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