# Biology Guided Therapy Recommendations for Treatment Determination of Hormone Receptor-Positive Advanced, Unresectable or Metastatic Breast Cancer, ENDORSE Trial

> **NCT07590583** · PHASE1 · NOT_YET_RECRUITING · sponsor: **City of Hope Medical Center** · enrollment: 20 (estimated)

## Conditions studied

- Advanced Hormone Receptor-Positive Breast Carcinoma
- Anatomic Stage III Breast Cancer AJCC v8
- Anatomic Stage IV Breast Cancer AJCC v8
- Metastatic Hormone Receptor-Positive Breast Carcinoma
- Unresectable Hormone Receptor-Positive Breast Carcinoma

## Interventions

- **PROCEDURE:** Biopsy Procedure
- **PROCEDURE:** Biospecimen Collection
- **PROCEDURE:** Bone Scan
- **PROCEDURE:** Computed Tomography
- **OTHER:** Electronic Health Record Review
- **PROCEDURE:** Magnetic Resonance Imaging
- **PROCEDURE:** Positron Emission Tomography
- **OTHER:** Treatment Planning
- **OTHER:** Treatment Regimen

## Key facts

- **NCT ID:** NCT07590583
- **Lead sponsor:** City of Hope Medical Center
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-12-19
- **Primary completion:** 2027-12-02
- **Final completion:** 2027-12-02
- **Target enrollment:** 20 (ESTIMATED)
- **Last updated:** 2026-05-15

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07590583

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07590583, "Biology Guided Therapy Recommendations for Treatment Determination of Hormone Receptor-Positive Advanced, Unresectable or Metastatic Breast Cancer, ENDORSE Trial". Retrieved via AI Analytics 2026-06-22 from https://api.ai-analytics.org/clinical/NCT07590583. Licensed CC0.

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