# A Phase II Study of AK146D1 Combined With AK112 in Advanced Breast Cancer

> **NCT07591090** · PHASE2 · NOT_YET_RECRUITING · sponsor: **Akeso** · enrollment: 200 (estimated)

## Conditions studied

- Advanced Breast Cancer

## Interventions

- **DRUG:** AK146D1 for injection
- **DRUG:** AK112 Injection

## Key facts

- **NCT ID:** NCT07591090
- **Lead sponsor:** Akeso
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-06-01
- **Primary completion:** 2027-09-01
- **Final completion:** 2029-02-04
- **Target enrollment:** 200 (ESTIMATED)
- **Last updated:** 2026-05-15


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07591090

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07591090, "A Phase II Study of AK146D1 Combined With AK112 in Advanced Breast Cancer". Retrieved via AI Analytics 2026-09-01 from https://api.ai-analytics.org/clinical/NCT07591090. Licensed CC0.

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