# Designation of 4-Piperidone as a List I Chemical
> **Proposed Rule** · Notice of proposed rulemaking. · Published 2022-09-22 · 87 FR 57852
## Document
- **Document number:** 2022-19974
- **Category:** other
- **Type:** Proposed Rule
- **Action:** Notice of proposed rulemaking.
- **Citation:** 87 FR 57852
- **Publication date:** 2022-09-22
## Abstract

The Drug Enforcement Administration is proposing the control of 4-piperidone, its acetals, its amides, its carbamates, its salts, and salts of its acetals, its amides, and its carbamates, whenever the existence of such is possible, as a list I chemical under the Controlled Substances Act. The Drug Enforcement Administration finds that 4-piperidone is used in the illicit manufacture of the controlled substance fentanyl, and is important to the manufacture of the controlled substance fentanyl because it cannot be replaced by other chemicals in its respective synthetic pathways which are used in the illicit manufacture of fentanyl. If finalized, this action would subject handlers of 4-piperidone to the chemical regulatory provisions of the Controlled Substances Act and its implementing regulations. This rulemaking does not establish a threshold for domestic and international transactions of 4-piperidone. As such, all transactions of chemical mixtures containing 4-piperidone will be regulated at any concentration and will be subject to control under the Controlled Substances Act.

## Source
- [Federal Register document](https://www.federalregister.gov/documents/2022/09/22/2022-19974/designation-of-4-piperidone-as-a-list-i-chemical)
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