The Nuclear Regulatory Commission (NRC) is amending its regulations revising the NAC International Multi-Purpose Canister (NAC- MPC) cask system listing within the "List of Approved Spent Fuel Storage Casks" to include Amendment 2 to Certificate of Compliance (CoC) Number 1025. This amendment will allow for modification of the design of the cask system to accommodate a new type of fuel. The NAC- MPC system component modifications include increased length of the fuel basket and canister, transfer cask, and vertical concrete cask. Changes also include a redesigned fuel basket to accommodate 26 fuel assemblies, with an alternate 24-fuel assembly configuration and increased transfer cask radial shielding. The CoC has been revised in its entirety to include a reference to the new type of fuel and a revised format. The Technical Specifications (TS) have also been revised in their entirety to include specifications for the new type of fuel, new operational limits, and to incorporate a revised format for the TS.