Pfizer, Inc. (ÂPfizerÂ) operates a Global Manufacturing facility in Groton, Connecticut that is primarily engaged in the manufacture of pharmaceuticals using solvent-based production techniques. Pfizer utilizes pressure testing as a means of leak detection and repair (LDAR) to control volatile organic compound (VOC) and hazardous air pollutant (HAP) emissions from the two production lines. On numerous occasions Pfizer failed to comply with PharmaMACT requirements.