# Ledprona Double-Stranded RNA; Exemption From the Requirement of a Tolerance
> **Rule** · Final rule. · Published 2023-10-05 · Effective 2023-10-05 · 88 FR 69039
## Document
- **Document number:** 2023-22199
- **Category:** pesticide
- **Federal Register citation:** 88 FR 69039
- **CFR reference:** 40 CFR 180
- **Publication date:** 2023-10-05
- **Effective date:** 2023-10-05
- **EPA docket:** EPA-HQ-OPP-2021-0269
## Abstract

This regulation establishes an exemption from the requirement of a tolerance for residues of Ledprona double-stranded (ds) RNA in or on potato when used as a foliar-applied insecticide for the selective control of Colorado potato beetle and in accordance with label directions and good agricultural practices. GreenLight Biosciences, Inc. submitted a petition to EPA under the Federal Food, Drug, and Cosmetic Act (FFDCA), requesting an exemption from the requirement of a tolerance. This regulation eliminates the need to establish a maximum permissible level for residues of Ledprona dsRNA under FFDCA when used in accordance with this exemption.

## Source
- [Federal Register document](https://www.federalregister.gov/documents/2023/10/05/2023-22199/ledprona-double-stranded-rna-exemption-from-the-requirement-of-a-tolerance)
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