# Core D: Computational

> **NIH NIH U19** · UNIVERSITY OF CALIFORNIA LOS ANGELES · 2020 · $119,081

## Abstract

CORE D: Computational
SUMMARY/ABSTRACT
This U19 application proposes three research Projects and four Cores for shared resources initiated and led by
investigators at the University of California Los Angeles (UCLA) and the University of California San Francisco
(UCSF), centered around the theme of mapping CMV immune responses in solid organ transplantation. The
Computational Core provides computational expertise required for the proper analysis and network modelling
of data generated by other Cores and Projects. Services will be provided in the following areas:
  Central infrastructure for data preprocessing of high throughput molecular data
  Dimensionality reduction methodologies for data interpretation and increasing predictive power.
  Leverage pathway analysis to interpret RNA sequencing data.
  Statistical methodologies for interpreting multivariate data and identify predictive features.
  Modeling the lymphocyte and viral dynamics to interpret immune-phenotyping datasets.
  Assistance with education of consortium members and manuscript preparation.

## Key facts

- **NIH application ID:** 10000880
- **Project number:** 5U19AI128913-04
- **Recipient organization:** UNIVERSITY OF CALIFORNIA LOS ANGELES
- **Principal Investigator:** Alexander Hoffmann
- **Activity code:** U19 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $119,081
- **Award type:** 5
- **Project period:** 2017-08-01 → 2022-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10000880

## Citation

> US National Institutes of Health, RePORTER application 10000880, Core D: Computational (5U19AI128913-04). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10000880. Licensed CC0.

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