# X-ray Scattering

> **NIH NIH P30** · BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB · 2020 · $494,312

## Abstract

Abstract – X-ray Scattering Technology Core 
The X-ray Scattering Technology Core will provide user access to solution scattering and microbeam 
diffraction measurements at the Life Science X-ray Scattering (LiX) beamline and will continue to 
improve instrumentation reliability and the user experience at the beamline. We aim to achieve these 
goals by working on multiple fronts. We will provide HDF5 data packaging and user interfaces for data 
collection, browsing, processing and analysis. We will implement a Sample Manager for tracking 
samples and data, and for scheduling measurements and define data processing data flow. We will also 
work on software utilities to facilitate measurement automation, performance optimization and failure 
recovery. These capabilities will enable us to offer remote access and mail-in data collection for solution 
scattering, and to achieve a higher level of automation and therefore throughput with microbeam 
mapping. In addition to standard data analysis packages for solution scattering, enhanced capabilities 
for data analysis will be realized by making available at the beamline computer simulations for 
structural analysis on flexible structures and working with the user community to expand the data 
analysis library for microbeam mapping. Capabilities for time-resolved solution scattering will be 
acquired through collaboration and externally-funded research and made available to the all users. We 
will familiarize the user community with these beamline capabilities through hands-on training classes 
and workshops on advanced topics. Routine quality-assurance checks will be performed to monitor 
instrument performance and to resolve issues before they impact beamline operations. Equipment 
pools shared with other beamlines under this proposal and within National Synchrotron Light Source 
II (NSLS-II) will provide spare components in case of emergency to allow time for repair and recovery. 
To maintain the competitiveness of the beamline, we propose to complete the LiX mutlilayer 
monochromator, to provide higher beam intensity at the sample and the flexibility of trading beam 
intensity for smaller beam size or better beam stability.

## Key facts

- **NIH application ID:** 10002292
- **Project number:** 5P30GM133893-02
- **Recipient organization:** BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB
- **Principal Investigator:** Lin Yang
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $494,312
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10002292

## Citation

> US National Institutes of Health, RePORTER application 10002292, X-ray Scattering (5P30GM133893-02). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10002292. Licensed CC0.

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