# Tissue Resource and Morphology Core (TRMC)

> **NIH NIH U54** · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2020 · $109,821

## Abstract

Abstract:
Results from tissue culture and animal models provide important information, but must be validated in human
tissue to be considered clinically relevant. Thus, the success of this O'Brien Center will depend upon the
availability of high quality, appropriately selected human tissue specimens. The Tissue Resources and
Morphology Core (TRMC) will supply such material. The TRMC will be based on the Health Sciences Tissue
Bank, a core facility that has been accruing prostate tissue from BPH patients for over 15 years. The Director
of the Health Sciences Tissue Bank, Dr. Rajiv Dhir, a board certified pathologist with training in genitourinary
pathology, will serve as the TRMC Director. Dr. Dhir will assure the proper use and analysis of BPH
specimens in the proposed projects. The TRMC will provide an array of services: (1) Procurement of normal
and diseased prostates and bladders; (2) Banking of specimens; (3) Data collection to annotate samples,
specimen data entry, and inventory management; (4) Morphology support for appropriate case selection for the
proposed studies; (5) Histology support and immunohistochemistry. Tissue microarray development will be
done for high throughput assessment, if needed. (6) Support and assistance for Institutional Review Board
issues.

## Key facts

- **NIH application ID:** 10002342
- **Project number:** 5U54DK112079-05
- **Recipient organization:** UNIVERSITY OF PITTSBURGH AT PITTSBURGH
- **Principal Investigator:** RAJIV DHIR
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $109,821
- **Award type:** 5
- **Project period:** 2016-09-22 → 2022-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10002342

## Citation

> US National Institutes of Health, RePORTER application 10002342, Tissue Resource and Morphology Core (TRMC) (5U54DK112079-05). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10002342. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*