# Boston Intellectual and Developmental Disabilities Research Center

> **NIH NIH U54** · BOSTON CHILDREN'S HOSPITAL · 2020 · $1,008,532

## Abstract

ABSTRACT
This Center grant requests funding for six core facilities; Administrative, Clinical/Translational,
Cellular Imaging, Mouse Neurodevelopmental Behavior, Mouse Gene Manipulation and
Molecular Genetics, to support a broadly-based research program in intellectual and
developmental disabilities at Boston Children's Hospital and Harvard Medical School. Our
specific aims are to: 1) Maintain and introduce new “state of the art” core facilities that can be
shared by Intellectual and Developmental Disabilities Research Center (IDDRC) investigators,
providing core research services not possible in a single laboratory; 2) Use the framework of the
core laboratories to enhance and encourage collaboration between IDDRC investigators; 3)
Provide core services to aid in the training of young investigators and trainees and 4) Use the
core services provided by the IDDRC program to leverage collaboration outside the institution,
particularly with other IDDRCs, to speed the development of effective clinical interventions in
intellectual and developmental disabilities. The Center supports 105 research projects and 64
investigators who receive approximately $71M in external funding, $46M of which is from the
NIH. Research in the Center occurs in over 125,000 sq.ft. of space in research buildings at
Boston Children's Hospital and Harvard Medical School affiliated institutions in the Harvard
Longwood Medical Area. Our research focuses on three programmatic areas- Basic
Neuroscience, Clinical / Translational Neuroscience and Genetics- and our primary goal is to
identify the causes of and develop therapies for children with intellectual and developmental
disabilities. The research of this IDDRC encompasses laboratory research on fundamental
processes of normal and abnormal neurodevelopment and plasticity, as well as clinical and
behavioral studies directed at disorders including, but not limited to, autistic spectrum disorders,
brain injury, neuro-oncology, learning and cognitive disabilities, the effects of surgery and
environmental toxins on neural development, and multiple neurogenetic disorders, including
those that affect neural formation, migration, specification and synaptic connectivity, as well as
muscular dystrophy.

## Key facts

- **NIH application ID:** 10003034
- **Project number:** 5U54HD090255-05
- **Recipient organization:** BOSTON CHILDREN'S HOSPITAL
- **Principal Investigator:** SCOTT Loren POMEROY
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $1,008,532
- **Award type:** 5
- **Project period:** 2016-09-23 → 2021-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10003034

## Citation

> US National Institutes of Health, RePORTER application 10003034, Boston Intellectual and Developmental Disabilities Research Center (5U54HD090255-05). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10003034. Licensed CC0.

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