# URBAN ARCH (1/5) Administrative Coordinating Core (Admin Core)

> **NIH NIH U24** · BOSTON MEDICAL CENTER · 2020 · $366,900

## Abstract

Project Summary
Due to improved HIV treatment and access to antiretroviral therapy (ART), people living with HIV are living
longer, which has resulted in an increase in comorbidities. Unhealthy alcohol use is prevalent in this population
and is associated with increased risk and worse outcomes for multiple adverse health conditions, including
tuberculosis [TB], cardiovascular disease [CVD], and falls. Over the past 5 years, the Uganda Russia Boston
Alcohol Network for Alcohol Research Collaboration on HIV/AIDS (URBAN ARCH) Consortium created
cohorts of people living with HIV and investigated the complex relationship between alcohol use and HIV.
Through domestic and international collaborations, URBAN ARCH investigators, including specialists in
epidemiology, internal medicine, addiction medicine, HIV/AIDS, infectious diseases, psychiatry, and
biostatistics, have focused on how alcohol use affects HIV clinical manifestations and how treatments beyond
ART mitigate alcohol-related harms. The central theme of the URBAN ARCH Consortium for the next 5 years
is to examine the consequences of alcohol use on comorbidities among people living with HIV so as to
increase availability of treatments and improve outcomes.
URBAN ARCH will build upon existing cohorts of people living with HIV in Uganda, Russia, and Boston with
their well-characterized alcohol consumption patterns to embark on important new research initiatives. This
global research is aligned with the Office of AIDS Research's highest HIV/AIDS research priorities (i.e.,
prevention and treatment of HIV-related comorbidities and complications, including TB [Uganda], CVD
[Russia], and falls [Boston]).The goal of the Administrative Core is to ensure that the scientific and
programmatic activities of the URBAN ARCH Consortium are carried out with high quality and timeliness. The
Administrative Core will use the latest technologies to maximize the overall productivity of the URBAN ARCH
Consortium and assist with the fostering of multidisciplinary collaborations to promote innovative and rigorous
HIV/alcohol research. The following are the Specific Aims of the Administrative Core:
  Promote a collaborative, integrated approach to research goals;
  Facilitate communication and collaboration between all Consortium components;
  Coordinate and prioritize access to resources including the URBAN ARCH data and sample repository;
  Assess components' progress and quality to maximize the scientific impact of the Consortium; and
  Encourage the sharing of data with investigators within and outside the Consortium.
The success of URBAN ARCH will be critically dependent on the Administrative Core's scientific and
administrative leadership to integrate and capitalize on the Consortium's outstanding collaborators, resources,
cohorts and research capabilities.

## Key facts

- **NIH application ID:** 10003117
- **Project number:** 5U24AA020778-10
- **Recipient organization:** BOSTON MEDICAL CENTER
- **Principal Investigator:** JEFFREY H. SAMET
- **Activity code:** U24 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $366,900
- **Award type:** 5
- **Project period:** 2011-09-20 → 2022-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10003117

## Citation

> US National Institutes of Health, RePORTER application 10003117, URBAN ARCH (1/5) Administrative Coordinating Core (Admin Core) (5U24AA020778-10). Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/grant/nih/10003117. Licensed CC0.

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