# Addressing Low Vision due to Severe Peripheral Field Loss: Development and Validation of a Patient-Centered Outcome Measure

> **NIH NIH K23** · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 2020 · $232,894

## Abstract

Abstract
The burden of blindness and visual impairment in the United States is expected to double between 2015 and
2050 to 8.96 million people. Blacks, Hispanics and older individuals will be disproportionally affected, further
accentuating the disparate impact of vision disorders. Although low vision rehabilitation (LVR) has been shown
to improve the functioning of patients, considerable opportunities remain to better understand and overcome
functional limitations due to low vision. Specifically, the effectiveness of LVR for patients with peripheral field
loss (PFL) has not been well-studied, though 15-20% of patients presenting for LVR have glaucoma or a retinal
degeneration, two important causes of PFL. In order to evaluate and compare interventions for this population,
a highly relevant measure of functioning is needed. The proposed project will address this through the
development and validation of a patient-reported outcome measure, the Low Vision Severely Constricted
Peripheral Eyesight (LV-SCOPE) Assessment. In Aim 1 of this proposal, focus groups with patients, caretakers
and vision providers will identify the impairments and LVR goals associated with severe PFL. Since PFL often
exists in combination with visual acuity loss, patients with PFL and a range of visual acuities will be included.
We anticipate that PFL will preferentially impact known functions of the dorsal visual processing stream, as this
pathway depends on peripheral vision for spatial awareness and motor behavior. In Aim 2, focus group data
will guide the selection of survey items for the outcome measure. In Aim 3, psychometric evaluations will test
the validity, reliability and precision of the LV-SCOPE. Once validated, the LV-SCOPE may be an optimal
outcome measure to evaluate and identify targeted LVR strategies for patients with PFL, a sizable
understudied population. This project directly addresses the National Eye Institute's low vision priority research
area “to create and validate vision tests relevant for the tasks of daily living.” Dr. Ehrlich's long-term career goal
is to improve the vision-dependent functioning of patients with low vision. He will achieve this through
coursework, mentorship and research to improve the measurement of functional impairment and facilitate the
evaluation of targeted LVR strategies. The applicant's training plan is a natural progression from his
background in ophthalmology, clinical research and public health. He will acquire knowledge and expertise in
outcome measure development and psychometrics, low vision and rehabilitation, mixed-methods analyses and
clinical trials. Dr. Ehrlich has devised a plan of pertinent coursework, individualized mentorship, and directed
self-study to achieve his training and research goals. Dr. Ehrlich's career development will benefit from the vast
resources of the University of Michigan and the support of his mentors, including Drs. Noelle Carlozzi, Paul
Lee, Robert Massof and Joan Stelmack. This pro...

## Key facts

- **NIH application ID:** 10003258
- **Project number:** 5K23EY027848-04
- **Recipient organization:** UNIVERSITY OF MICHIGAN AT ANN ARBOR
- **Principal Investigator:** Joshua Robert Ehrlich
- **Activity code:** K23 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $232,894
- **Award type:** 5
- **Project period:** 2017-09-01 → 2022-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10003258

## Citation

> US National Institutes of Health, RePORTER application 10003258, Addressing Low Vision due to Severe Peripheral Field Loss: Development and Validation of a Patient-Centered Outcome Measure (5K23EY027848-04). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10003258. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*
