# Pilot Core

> **NIH NIH P50** · CHILDREN'S HOSP OF PHILADELPHIA · 2020 · $150,560

## Abstract

PILOT AND FEASIBILITY PROGRAM
ABSTRACT
The Pilot and Feasibility program will be a central and cohesive piece of the Pediatric Center of Excellence. The
overall goal of the Pilot and Feasibility Program is to develop the science of investigators who need to obtain
preliminary data to inform the design of future clinical trials in children with kidney disease. The Pilot and
Feasibility Program will work closely with the Administrative Core, the Design/Analysis Core, the Clinical
Phenotyping Core, and the Learning Health System Core to publicize, elicit, review, and fund proposals. The
Pilot and Feasibility program will promote collaboration with investigators outside The Children's Hospital of
Philadelphia and our regional academic partners at Johns Hopkins University. We will fund 2-4 pilot projects
during the award period, with each project receiving $50,000 in direct support per year for a maximum of two
years. At least one proposal will be funded from outside the research base. Additionally, the Department of
Pediatrics at the Children’s Hospital of Philadelphia has generously agreed to fund an extra Pilot study at $50,000
per year for two years. All pilot and feasibility projects will be chosen meritoriously through peer review by a
Scientific Advisory Committee. The Pilot and Feasibility Program will offer mentoring, through the formation of
sub-committees, for those investigators who need input on their research projects throughout the submission
and review process. To achieve the following specific aims and accomplish the overall research goals of the
Pediatric Center of Excellence, each Pilot and Feasibility study will make use of the resources provided by at
least one of the Center’s three Cores. The Specific Aims of the Pilot and Feasibility Program are: 1) To stimulate
and solicit new project ideas that support the overall research goal of the Pediatric Center of Excellence–namely
to decrease the barriers to implementing clinical trials in children with kidney disease; 2) To encourage
submission of pilot project proposals by junior investigators and to mentor these investigators in the revision of
their proposals, as needed; 3) To review pilot project submissions for their scientific merit, level of innovation,
and cohesion with the overall research goals and three Cores of the Pediatric Center of Excellence; and 4) To
promote the development of new research directions, acquiring preliminary data that will be the foundation for
applications for future independent research support in clinical trials. The Pilot and Feasibility Program will build
upon the strong pediatric nephrology research experience at the Children’s Hospital of Philadelphia, the
outstanding talent from the broader local scientific community at the University of Pennsylvania, and the regional
expertise offered by Johns Hopkins University. We anticipate that the selected pilot projects will provide
investigators the opportunity to generate preliminary data that will for...

## Key facts

- **NIH application ID:** 10003862
- **Project number:** 5P50DK114786-04
- **Recipient organization:** CHILDREN'S HOSP OF PHILADELPHIA
- **Principal Investigator:** SUSAN L. FURTH
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $150,560
- **Award type:** 5
- **Project period:** 2017-09-18 → 2022-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10003862

## Citation

> US National Institutes of Health, RePORTER application 10003862, Pilot Core (5P50DK114786-04). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10003862. Licensed CC0.

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