# Clinical Research Design, Epidemiology, and Biostatistics Core

> **NIH NIH U54** · WEST VIRGINIA UNIVERSITY · 2020 · $293,110

## Abstract

The overall purpose of the Clinical Research Design, Epidemiology and Biostatistics (CRDEB) Core of the West 
Virginia Clinical and Translational Science Institute (WVCTSI) is to provide investigators throughout West 
Virginia (WV) with a centrally coordinated means of analytics support. This expertise will be delivered from a 
group of scientists that collectively bring a comprehensive set of skills ranging from general to highly specialized 
expertise in biostatistics and epidemiology. The goal is to enable investigators to rigorously address WVCTSI 
priority health areas that include: addiction & emerging epidemics (e.g., hepatitis C), cancer, cardiovascular 
disease, and chronic lung disease. We propose the following three specific aims: 1) effectively engage 
investigators throughout WV by providing traditional services in biostatistics and epidemiology, 2) implement 
cutting-edge tools and methods in biostatistics and epidemiology, with a particular focus on the needs of WV 
researchers, and 3) disseminate current and classical information in biostatistics and epidemiology. Statistics 
assistance will be provided to researchers via one-on-one consulting as well as walk-in clinics. Given the distance 
between institutions in WV, these consultations can occur either in-person or via phone, e-mail, Skype, etc. New 
methods for designing studies and analyzing data will focus on those most relevant to West Virginia and include 
adaptive response designs, predictive modeling, and clinical and population health epidemiology, making use of 
new data linkage capabilities. Methods focused on the conduct of “real world” studies that can be conducted 
quickly and have a direct and immediate impact on the citizens of West Virginia will also be a major priority of 
this Core. To help achieve this goal, experts from throughout the United States will be invited to share their 
expertise with WV statisticians who can then apply these methods to locally collected data. To enhance the 
statistical knowledge base in WV, statisticians included in this project will offer seminars and workshops to 
investigators conducting research in WV. CRDEB faculty will also provide instruction in certificate and degree 
programs aimed at improving the research capacity in West Virginia. The ultimate goal of all of these activities 
is improving the health of all West Virginians.

## Key facts

- **NIH application ID:** 10004064
- **Project number:** 5U54GM104942-05
- **Recipient organization:** WEST VIRGINIA UNIVERSITY
- **Principal Investigator:** THOMAS C HULSEY
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $293,110
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10004064

## Citation

> US National Institutes of Health, RePORTER application 10004064, Clinical Research Design, Epidemiology, and Biostatistics Core (5U54GM104942-05). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10004064. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*