# Project-002

> **NIH NIH U54** · UNIVERSITY OF NORTH DAKOTA · 2020 · $181,941

## Abstract

Summary: The objective of this grant application is to create a center to support and expand our ability to
conduct full-spectrum clinical and translational research on various cancers. Establishing the Dakota
Cancer Collaborative on Translational Activity (DACCOTA) will also allow us for the first time to apply our
basic scientific and epidemiologic work to the clinical arena while training clinician-investigator partners to
translate these discoveries. We will train basic scientists to conduct translational work, population health
experts to understand the community determinants of cancer outcomes, and clinicians to collaborate. The
DACCOTA will promote and facilitate interactions between clinicians and scientists with unique but
complementary areas of expertise. Our goal is to develop a highly productive, collaborative, and
sustainable translational research center that will focus on the cancers that most commonly and
disproportionately afflict the citizens of our region, especially American Indians. We have proposed
independent cores, all led by capable investigators, that will assist in building a competitive clinical and
translational cancer research center. The DACCOTA will provide an academic home for clinical and
translational scientists and trainees. These investigators will focus on understanding the mechanisms
leading to the initiation and progression of cancer, which will facilitate the development of novel and
effective treatments and improve disease surveillance. This is necessary due to the increase in cancer
prevalence and mortality in the Dakota region and throughout the USA. The DACCOTA will have further
impact by validating new ways of developing and supporting individuals to facilitate team-based science
addressing critical issues affecting the region. Our Professional Development Core will develop aspiring
investigators and train practicing "real world“ clinicians to become more avid and effective collaborators.
Applicants for pilot grants will be required to propose teams including an investigator and clinician. The
Community Enagement and Outreach Core will help recruit volunteers, seek advice about overall
directions, and work with community leaders to designate specific cancer-related issues of community
concern for RFA’s that will be funneled through the Pilot Projects Program. In addition to the community-based
natures of the University of North Dakota (UND), North Dakota State University (NDSU), and the
University of South Dakota (USD), the collaborating hospitals in this proposal cover more than 90% of the
region and include multiple innovative departments of family and community medicine as well as rural and
population health. There are also three MPH programs between these institutions. Thus, we are superbly
positioned to conduct clinical research encompassing the entire region. Similarly, the Biostatistics,
Epidemiology, and Research Design Core and the Clinical Research Resources and Facilites Core will
combine t...

## Key facts

- **NIH application ID:** 10004134
- **Project number:** 5U54GM128729-03
- **Recipient organization:** UNIVERSITY OF NORTH DAKOTA
- **Principal Investigator:** MARC D. BASSON
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $181,941
- **Award type:** 5
- **Project period:** 2018-09-01 → 2023-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10004134

## Citation

> US National Institutes of Health, RePORTER application 10004134, Project-002 (5U54GM128729-03). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10004134. Licensed CC0.

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