PROJECT ABSTRACT Hopa Mountain, working in partnership with Montana State University (MSU), will develop innovative and coordinated opportunities for Montana youth to strengthen their STEM (Science, Technology, Engineering and Mathematics) skills and knowledge while preparing them for higher education and careers in health sciences. The overall project goal of HealthMakers is to support rural and tribal youth’s interest and exposure to careers in the sciences while giving them the skills and resources to play leadership roles in increasing healthy family practices in their homes and communities. HealthMakers will achieve meaningful impacts annually through four strategies: (1) Health-focused college preparation programs for 50 teens; (2) Summer academic enrichment programs for 20 teens; (3) Community-based science literacy events for 2,000 children and their families, and (4) Professional development for educators, community members, and parents. Hopa Mountain and MSU will engage youth, educators, community leaders, and parents in training opportunities through HealthMakers. Participants will take part in community-based workshops, college tours, and summer institutes led by MSU faculty, healthcare professionals, Hopa Mountain staff, and their peers. Through these strategic aims, HealthMakers will help create a stronger workforce and inspire students to pursue careers in the sciences.