# Biostatistics and Bioinformatics

> **NIH NIH P50** · UNIVERSITY OF TX MD ANDERSON CAN CTR · 2020 · $264,546

## Abstract

PROJECT SUMMARY (Biostatistics and Bioinformatics Core) 
The research proposed in The MD Anderson Cancer Center Prostate Cancer SPORE encompasses a broad 
range of activities, including studies of cell lines and animal models and clinical trials. These studies will 
generate many different types of data, including clinical, epidemiological, biochemical, immunohistochemical, 
pharmacokinetic, genotypic, and immunologic data. The Biostatistics and Bioinformatics Core for the Prostate 
Cancer SPORE has been a comprehensive resource for the biostatistic and bioinformatic needs that arise 
within the SPORE. This resource has the flexibility to match personnel with the evolving needs of the SPORE 
projects. We are able to incorporate sound experimental design principles within each project to enhance the 
interpretability of the study results, carry out data analyses using appropriate statistical methodology, and 
contribute to the interpretation of results via written reports and frequent interaction with project investigators. 
We can match core personnel with the expertise required in a specific area of a SPORE project to efficiently 
meet the ongoing needs of the multiple components of the projects. The specific aims of the Biostatistics and 
Bioinformatics Core are as follows. 1) Provide guidance in the design and conduct of clinical trials and other 
experiments (including high-dimensional genomic and proteomic studies) arising from the ongoing research of 
the SPORE. 2) Provide innovative and tailored statistical modeling, simulation techniques, and data analyses 
as needed for the main projects, developmental research and career development projects, and other cores to 
achieve their specific aims. 3) Ensure that the results of all projects are based on well-designed experiments 
and are appropriately interpreted. 4) Provide guidance in the design and use of an information system to store 
appropriate data generated by all projects; develop integrated computational libraries and tools for producing 
documented, reproducible statistical and bioinformatic analyses; and support the use of these tools for 
analyses conducted by and on behalf of the projects.

## Key facts

- **NIH application ID:** 10005145
- **Project number:** 5P50CA140388-10
- **Recipient organization:** UNIVERSITY OF TX MD ANDERSON CAN CTR
- **Principal Investigator:** KIM-ANH DO
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $264,546
- **Award type:** 5
- **Project period:** 2009-09-02 → 2023-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10005145

## Citation

> US National Institutes of Health, RePORTER application 10005145, Biostatistics and Bioinformatics (5P50CA140388-10). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10005145. Licensed CC0.

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