# Core 1 - Acquisition

> **NIH NIH P30** · UNIVERSITY OF MINNESOTA · 2020 · $200,504

## Abstract

Magnetic Resonance (MR) Imaging (MRI) and Spectroscopy (MRS) are among the most powerful
tools to investigate brain structure, function and neurochemistry. The richness and accuracy of these
structural, functional and neurochemical information are critically linked to data quality, for which high
and ultra-high systems offer major advantages, notably superior signal-to-noise ratio (SNR), spatial and
spectral resolution. The goal of this Core is to accelerate, broaden and enhance a large array of
ambitious neuroscience research, providing necessary support and infrastructure to allow a large
community of NINDS funded investigators to benefit from advanced MRI and MRS methodologies and
instrumentation to study brain structure and function. This Core will thus expand the access for
neuroscientists, to the exceptional high and ultrahigh field MR resources available at CMRR, including
seven human MR systems operating at 3T (x3), 4T, 7T (x2) and 10.5T, and two animals MR systems
operating at 9.4T and 16.4T. We propose the following specific aims: Aim 1: To provide technical
expertise and assistance in acquiring MRI and multinuclear MRS data to support brain research in
humans and animals in vivo. Aim 2: To provide expertise in programming specialized MRI and MRS
pulse sequences, and in optimizing sequence and acquisition protocol parameters for experimental
needs of projects supported by the NINDS Institutional Center Cores for both human (3T, 4T, 7T,
10.5T) and animal (9.4T, 16.4T) systems on instruments operated with Varian or Siemens platforms.
Aim 3: To build, maintain and customize high performance multi-channel RF coils for human and
animal studies, compatible with stimulus presentation, monitoring device or other required experimental
equipment, in order to enable large scale MR data acquisition on all systems, while performing RF coil
and scanner quality control and ensuring subject safety.

## Key facts

- **NIH application ID:** 10005498
- **Project number:** 5P30NS076408-09
- **Recipient organization:** UNIVERSITY OF MINNESOTA
- **Principal Investigator:** Pierre-Francois VAN DE MOORTELE
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $200,504
- **Award type:** 5
- **Project period:** — → 2022-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10005498

## Citation

> US National Institutes of Health, RePORTER application 10005498, Core 1 - Acquisition (5P30NS076408-09). Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/grant/nih/10005498. Licensed CC0.

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