# Core 1: Biostatistics Core

> **NIH NIH P50** · JOHNS HOPKINS UNIVERSITY · 2020 · $106,630

## Abstract

PROJECT SUMMARY
The goal of the GastroIntestinal Biostatistics and Bioinformatics Core (GI-BBC) is to
provide wide-ranging, high-quality statistical and bioinformatics support to the GI
SPORE. The primary aim of the GI-BBC is to assist GI SPORE investigators in the
design, conduct and analysis of laboratory and clinical studies proposed in this SPORE
application. The GI-BBC will focus its efforts on assisting both the clinical and laboratory
investigators in translating their pre-clinic studies into clinical studies by providing state-
of-the-art experimental designs and analyses through statistical consultation and in
collaboration with respect to methodology, feasibility, analysis, and reporting of clinical
and laboratory studies. In addition, the GI-BBC will serve as an ongoing resource for all
GI-SPORE investigators. The Core will be led by Dr. Sugar and Dr. Scharpf and Dr.
Rachel Karchin will act as a co-investigator. These GI-BBC faculty members have
complementary areas of expertise: Dr. Sugar in biostatistics specializing in translation
and clinical study design and analysis, Dr. Scharpf in the analysis of high-throughput
genomic assays, Dr. Karchin in computational genetics. Ms. Amanda Blackford, a
biostatistician in the Cancer Center, will assist Drs. Sugar and Scharpf in statistical
analyses. David McKean, a Master's level bioinformatics specialist will assist Dr.
Scharpf. Centralization of statistical needs within the GI-BBC core will provide SPORE
investigators with open access to a team of statisticians with the skill set necessary to
meet the current and future goals of the SPORE in a cost-effective manner. In addition,
it will facilitate communication across SPORE projects, aiding the translation of research
findings into the clinical setting.

## Key facts

- **NIH application ID:** 10006159
- **Project number:** 5P50CA062924-26
- **Recipient organization:** JOHNS HOPKINS UNIVERSITY
- **Principal Investigator:** Elizabeth Ann Sugar
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $106,630
- **Award type:** 5
- **Project period:** 1997-02-28 → 2023-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10006159

## Citation

> US National Institutes of Health, RePORTER application 10006159, Core 1: Biostatistics Core (5P50CA062924-26). Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/grant/nih/10006159. Licensed CC0.

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