# Genome Technologies and Bioinformatics

> **NIH NIH P30** · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · 2020 · $233,760

## Abstract

SUMMARY for the Genome Technologies and Bioinformatics Core
The uniformly recognized significance of genomics and bioinformatics for the biomedical research community
is also reflected in needs expressed by VCIID faculty members. This core provides support in all aspects of
genomics, from the design stage, through data acquisition/quality assessment, and finally extensive
bioinformatics support. The core uses an Affymetrix GeneChip and Illumina HiSeq technologies for
oligonucleotide arrays and massively parallel sequencing, respectively. It is currently supporting projects for
11 COBRE faculty members, and has performed genomics data collection and analysis for 86 active COBRE
projects. Preliminary discussions are underway for new projects with 16 additional COBRE faculty members.
Accomplishments from Phases I and II include support for 28 publications, and addition of massively parallel
sequencing services.
Based on over 40 person-years of experience among the Core Directors leading core facilities, they identified
eight essential characteristics needed for the Core: qualified and experienced staff, state-of-the-art equipment,
education, responsiveness, process, experiment design, quality assessment, and sustainability. The Phase III
COBRE objectives of the Genome Technologies and Bioinformatics Core satisfy these essential
characteristics. Specific Aim 1 will provide state-of-the-art equipment, cutting-edge techniques, and
experienced personnel to enhance the research of the VCIID-COBRE. Specific Aim 2 will provide a wide
array of services to VCIID-COBRE faculty to facilitate their research. We will meet this goal by applying our
standard process to projects that includes oversight by a project manager, experiment design, defined
vocabulary, quality assessment, archival storage, and documentation. We have surveyed the user base, and
are prepared to offer efficient and effective service to support VCIID collaborations. Specific Aim 3 will
continue our Phase II plan for sustainability that includes a greatly expanded user base, both at UVM as well
as at several other campuses. We have developed a progressive fee-for-service structure, and are highly
responsive to the need for constant adaptation to changes in research needs. We have received strong
commitments for sustained support from the institution for at least five years beyond Phase III, and we will add
revenue streams based on VCIID collaborations that will sustain our core beyond Phase III.
Our aims and objectives reflect both the eight essential characteristics identified by our leadership and the
VCIID needs identified by a survey of the VCIID. These aims will facilitate the transition of the Core into a fully
self-sustainable facility capable of continuing to support state-of-the-art research.

## Key facts

- **NIH application ID:** 10006838
- **Project number:** 5P30GM118228-05
- **Recipient organization:** UNIVERSITY OF VERMONT & ST AGRIC COLLEGE
- **Principal Investigator:** JEFFREY P. BOND
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $233,760
- **Award type:** 5
- **Project period:** 2016-08-05 → 2023-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10006838

## Citation

> US National Institutes of Health, RePORTER application 10006838, Genome Technologies and Bioinformatics (5P30GM118228-05). Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/grant/nih/10006838. Licensed CC0.

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