# Resource-based Center for the Advancement of Precision Medicine in Rheumatology

> **NIH NIH P30** · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2020 · $721,693

## Abstract

PROJECT SUMMARY/ABSTRACT
The UCSF Resource-based Center for the Advancement of Precision Medicine in Rheumatology (P30)
will provide critically important resources and expertise to enable cutting-edge rheumatic disease research.
Given the emerging opportunities related to precision medicine, in conjunction with the significant
heterogeneity encompassed within the rheumatic diseases, our Center will focus on providing resources for
research that seeks to define underlying etiologic heterogeneity within and across rheumatic diseases by
applying new approaches and technology developed as part of the exciting field of precision medicine. UCSF
represents an ideal environment for the proposed P30 Center given tremendous institutional strengths in
immunology, genomics, molecular technologies, computational biology, and clinical research, including
engagement of at-risk populations and racial/ethnic minorities. In addition, UCSF is recognized as a leader in
clinical care of rheumatic disease patients across the age span, from childhood to old age. Further supporting
the rationale for investing in our Center are the substantial resources that can be leveraged at UCSF: sub-
specialty rheumatic disease clinics for lupus, rheumatoid arthritis, vasculitis, scleroderma, ankylosing
spondylitis, and pediatric rheumatic disease; the NIH-funded UCSF Multidisciplinary Clinical Research Center
(NIAMS P60) and Autoimmunity Center of Excellence (NIAID ACE); and the UCSF-Stanford Arthritis Center of
Excellence. To facilitate innovative and collaborative rheumatic disease research, our Center will include: 1) a
Human Subjects and Clinical Phenotyping Core co-directed by Drs. Patricia Katz and Jinoos Yazdany,
which will provide centralized coordination of subject recruitment, clinical phenotyping, and clinical data
collection and management (e.g., for electronic health record data, and patient or physician reported
outcomes); 2) a Genomics and Molecular Resources Core, co-directed by Drs. Pui-Yan Kwok and Lindsey
Criswell, which will provide centralized biospecimen processing and storage to facilitate access for more
researchers and provide consultation and coordination related to acquisition of genomics and molecular
phenotyping services; 3) an Integrative Bioinformatics Core, co-directed by Drs. Atul Butte and Marina
Sirota, which will provide computational and analytical expertise for study design, bioinformatics analysis of
clinical and molecular data, data integration and data dissemination; and 4) an Administrative Core directed
by Dr. Lindsey Criswell, with Dr. Mary Nakamura as associate director, which includes an enrichment program
designed to attract and support both young and experienced investigators through provision of pilot grants, a
mentoring program, educational seminars, and an annual symposium. These resources will meet the stated
needs of our research community and will have a major impact on advancing precision medicine research in
rheumatology by pr...

## Key facts

- **NIH application ID:** 10007596
- **Project number:** 5P30AR070155-05
- **Recipient organization:** UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- **Principal Investigator:** Mary C Nakamura
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $721,693
- **Award type:** 5
- **Project period:** 2016-09-21 → 2021-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10007596

## Citation

> US National Institutes of Health, RePORTER application 10007596, Resource-based Center for the Advancement of Precision Medicine in Rheumatology (5P30AR070155-05). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10007596. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*