# Core C  Cohort Administration and Biospecimen Core

> **NIH NIH P01** · HENRY FORD HEALTH SYSTEM · 2020 · $471,056

## Abstract

The purpose of the Cohort Administration and Biospecimen Core (Core C) is to provide coordination of efforts
and staff to facilitate the recruitment, enrollment, retention and sampling of participants in the new cohort; to
process, track and store participant biospecimens; and, to deliver stool and swab samples to Dr. Lynch's
laboratory at UCSF (Core D) for microbiome analyses, plasma samples to Dr. Ownby's laboratory at Georgia
University (Core E) for IgE analysis and stool and breastmilk samples to the Mass Spectrometry Core at
Michigan State University (MSU) for lipid analysis for this renewal project `Microbiota and Allergic Asthma
Precision Prevention' (MAAP2). This Core facility currently acts as the central processing laboratory and
clearinghouse for all biological and environmental samples obtained from study participants in the initial P01, the
`Microbes, Allergy, Asthma & Pets' (MAAP) study. This Core facility also serves as a repository for long-term
storage of specimens (plasma, breast milk, stool, urine, DNA, RNA, dust) for use in ongoing and future studies.
This laboratory has substantial experience performing all the tasks that are proposed for this Core in the present
proposal. The Cohort Administration and Biospecimen core is essential to the overall goals of this PPG
application as it represents the management and monitoring arm for the new birth cohort, whose samples will
inform all four projects. Core C will be responsible for programming and coordinating technical aspects of
recruitment and retention that provide Project Coordination staff with direction in these efforts. Core C will direct
the programmatic aspects of participant recruitment and retention that Project 1 and Project 2 will implement. In
addition, all projects will rely on Core C to process, track, store and ship the stool, swab, breastmilk and plasma
samples. By centralizing cohort management activities, the Cohort Administration and Biospecimen Core will
provide efficiency, consistency, and reliability. The centralization of biospecimen handling will provide skilled
laboratory staff experienced in the sample processing protocols, eliminating duplication of effort. Core C will
retain the programming staff needed for monitoring recruitment and retention, and for biospecimen identification,
storage, and distribution. The Core is under the leadership of Kim Woodcroft, PhD, who has 15 years of
experience in directing the Molecular Epidemiology Research Laboratory at HFHS. Christine Joseph, PhD, will
also provide leadership in the recruitment and retention monitoring aspects of the Core. Dr. Joseph has over a
decade of experience in observational studies and clinical trials, and in recruitment and retention of research
participants.

## Key facts

- **NIH application ID:** 10009266
- **Project number:** 5P01AI089473-07
- **Recipient organization:** HENRY FORD HEALTH SYSTEM
- **Principal Investigator:** Kimberley J Woodcroft
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $471,056
- **Award type:** 5
- **Project period:** 2012-07-06 → 2024-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10009266

## Citation

> US National Institutes of Health, RePORTER application 10009266, Core C  Cohort Administration and Biospecimen Core (5P01AI089473-07). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10009266. Licensed CC0.

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