# A Digital Therapeutic to Advance the Delivery of Effective Interventions for Suicide Prevention

> **NIH NIH R43** · OUI THERAPEUTICS, INC · 2020 · $481,035

## Abstract

ABSTRACT
Suicide is a top ten cause of death in the US and rates of suicide have increased steadily for the last twenty
years. Despite this, there is a paucity of research on treatment programs designed to reduce suicide attempts
and none that include a digital therapeutic. In this Phase I SBIR application Oui Therapeutics, LLC proposes a
project to: 1) create a beta version of the Oui app (called “Aviva”), a CBT-based digital therapeutic to reduce
the risk of suicide across diagnoses; and 2) to test the usability and feasibility of the Beta version of Aviva in a
single-group, open-label trial. The digital therapeutic being studied is built on face-to-face CBT treatment
protocols proven to be effective in clinical trials. Successful execution of the goals of this Phase I project will
generate a version of Aviva that is ready to be tested for efficacy with stabilized patients in a clinical trial. In the
long term, this project will have a beneficial impact on the field of suicide prevention through the development
of mobile technology designed to advance the delivery and dissemination of effective interventions.

## Key facts

- **NIH application ID:** 10010336
- **Project number:** 1R43MH123357-01
- **Recipient organization:** OUI THERAPEUTICS, INC
- **Principal Investigator:** Seth Feuerstein
- **Activity code:** R43 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $481,035
- **Award type:** 1
- **Project period:** 2020-07-23 → 2021-07-22

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10010336

## Citation

> US National Institutes of Health, RePORTER application 10010336, A Digital Therapeutic to Advance the Delivery of Effective Interventions for Suicide Prevention (1R43MH123357-01). Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/grant/nih/10010336. Licensed CC0.

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