# Live Animal Imaging and Functional Analysis Core

> **NIH NIH P30** · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · 2020 · $229,564

## Abstract

ABSTRACT 
Live Animal Imaging and Analysis Core 
Vision research requires the use of various animal models to investigate the mechanisms of visual 
development and degeneration, the pathogenesis of blinding infection and inflammation, and the efficacy of 
vision-saving therapeutics. The Live Animal Imaging and Analysis Core at the University of Oklahoma Health 
Sciences Center is responsible for providing vision researchers with state-of-the-art instrumentation in the 
physiology and function of vision in small animal models of development, degeneration, infection, and 
inflammation. These Cores support vision research on 15 NEI-funded R01 grants and other vision-related 
projects at OUHSC in two different locations within vivaria, which allows in/out privileges. More than 50 ocular 
disease models are being analyzed with electrophysiological, functional analysis, microscopy, and other 
support equipment in expanded research areas renovated specifically for this use. The instrumentation 
provided by this Core includes electroretinography (in vivo and ex vivo), optical coherence tomography, 
fundoscopy, optokinetics, laser photocoagulation, tonometry, indirect ophthalmoscopy, and slit lamp and 
biomicroscopic imaging. Environmental housing also includes equipment for light damage, dark rearing, 
hypoxia/hyperoxia, controlled humidity, and glaucoma models. Our Systems Managers are highly skilled in 
training personnel, assisting with experiments and data analysis, and maintaining core equipment to a quality 
standard. As such, this Core consolidates and provides instrumentation and expertise which would otherwise 
be too expensive or logistically difficult for vision researchers across campus to easily access. As in the 
previous funding period, this Core is motivated and committed to providing an effective, user-friendly, and high- 
quality research environment for all vision researchers at OUHSC.

## Key facts

- **NIH application ID:** 10011814
- **Project number:** 5P30EY021725-10
- **Recipient organization:** UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
- **Principal Investigator:** Michelle C Callegan
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $229,564
- **Award type:** 5
- **Project period:** 2011-09-01 → 2021-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10011814

## Citation

> US National Institutes of Health, RePORTER application 10011814, Live Animal Imaging and Functional Analysis Core (5P30EY021725-10). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10011814. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*