# Core B: Human Biology Validation Core

> **NIH NIH U54** · WEILL MEDICAL COLL OF CORNELL UNIV · 2020 · $279,116

## Abstract

Project summary/abstract
Human Core – Grinberg U54 CWOW
The Human Biology Validation core will provide vital research support to the CWOW. Neurodegenerative
disease pathology and genetics have become increasingly exciting and complex in recent years, with major
advances arising from work accomplished through this ADRC. In this renewal application, the Human Core will
be led by Dr. Lea T. Grinberg and Dr. Bruce L. Miller. Dr. Anne Fagan will lead a CSF array sub-core The
Human Core goals are to: (1) directly supporting this CWOW’s Projects (P) with well-characterized and
carefully treated human tissue, bio-fluids, and cells from tauopathy patients and controls; (2) validating the
relevance results from P 1-3 in human specimens; (3) developing enhanced tools for boosting the amount of
information retrieved for each single biospecimen samples. These core functions will support the aims of
Projects 1 (PI: Gan) and 3 (PI: Cuervo) by providing well-characterized human brain and bio fluid specimens
from tauopathies. Moreover, the Human Core will help to validate the findings from the CWOW’s projects to
accelerate translation from bench to clinical use.

## Key facts

- **NIH application ID:** 10011938
- **Project number:** 5U54NS100717-05
- **Recipient organization:** WEILL MEDICAL COLL OF CORNELL UNIV
- **Principal Investigator:** Lea Tenenholz Grinberg
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $279,116
- **Award type:** 5
- **Project period:** 2016-09-30 → 2023-02-28

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10011938

## Citation

> US National Institutes of Health, RePORTER application 10011938, Core B: Human Biology Validation Core (5U54NS100717-05). Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/grant/nih/10011938. Licensed CC0.

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