# Environmental Influences on Child Health Outcomes in the Northern Plains Safe Passage Study Cohort

> **NIH NIH UH3** · AVERA MCKENNAN · 2020 · $4,260,196

## Abstract

Project Summary/Abstract
 The overarching premise of this proposal is that the extant and proposed cohorts (n>4400), infrastructure,
and investigative team of PASS-ECHO are uniquely poised to answer questions relating to the impact of
prenatal and early childhood environmental exposures on later health outcomes. To accomplish this objective,
the study will build upon the successful study infrastructure established through the Prenatal Alcohol in SIDS
and Stillbirth (PASS) Network (NICHD U02-HD045935) and will utilize this unique cohort to provide a wealth of
prenatal and infant data that can expand the capability of the ECHO study in areas of neurodevelopment,
neurophysiology, and asthma, particularly among rural and American Indian youth. The PASS-ECHO
investigative team has a proven track record in conducting complex and high quality studies while maintaining
longitudinal participant and community engagement in the region. Complementary to the common protocol, the
PASS-ECHO cohort will examine in-depth data concurrent to individual-, family-, and social-level factors .While
this proposal focuses on neurodevelopmental and asthma outcomes, the PASS-ECHO cohort is capable of
including additional measures to provide additional data for the other ECHO focus areas. The PASS-ECHO
investigators, infrastructure, and cohort have the capacity to contribute significantly to meet the overarching
goal of ECHO.

## Key facts

- **NIH application ID:** 10011948
- **Project number:** 5UH3OD023279-06
- **Recipient organization:** AVERA MCKENNAN
- **Principal Investigator:** Amy J Elliott
- **Activity code:** UH3 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $4,260,196
- **Award type:** 5
- **Project period:** 2016-09-21 → 2023-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10011948

## Citation

> US National Institutes of Health, RePORTER application 10011948, Environmental Influences on Child Health Outcomes in the Northern Plains Safe Passage Study Cohort (5UH3OD023279-06). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10011948. Licensed CC0.

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