# UC Davis Alzheimer's Disease Core Center

> **NIH NIH P30** · UNIVERSITY OF CALIFORNIA AT DAVIS · 2020 · $69,900

## Abstract

PROJECT SUMMARY/ABSTRACT
African Americans (AA) and Latinos, the two largest minority groups in the U.S., are disproportionality affected
by Alzheimer's disease and related disorders (ADRD) as well as a number of other comorbid medical
conditions (e.g. hypertension, diabetes, etc.). There is evidence from population-based studies that general
rates of disability are higher among minorities, and thus Aim 1 will examine whether there are disparities in
instrumental activities of daily living (IADL) difficulties among AA and Latinos compared to Non-Hispanic
Whites. Understanding, preventing, and ameliorating potential health disparities is a major public health priority
because poorer functional outcomes translate into disparities in quality of life and greater economic burden.
Aim 2 will examine whether there are differences in key factors that are associated with functional abilities
across groups. Regardless of whether there are disparities in overall level of IADL disability, there are likely to
be different contributing factors (e.g., cognition, physical functioning, and medical co-morbidities). This study
will address an important gap in knowledge about potential disparities and contributors to functional outcomes,
which has important implications for developing effective public health policies and tailoring interventions. This
supplement would allow Dr. Chan to reduce her clinical responsibilities and increase her dedicated research
time, which would work towards her long-term career goal of developing an independent program of research
in ADRD related disparities among ethnic minorities. This supplement would also provide a mentored research
experience at the UCD Alzheimer's Disease Center that will further develop her experience in clinical research
methodology and produce peer-reviewed scientific publications on ADRD, which would enhance her existing
knowledge base of cognitive aging in minorities.

## Key facts

- **NIH application ID:** 10012518
- **Project number:** 3P30AG010129-29S2
- **Recipient organization:** UNIVERSITY OF CALIFORNIA AT DAVIS
- **Principal Investigator:** Charles DeCarli
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $69,900
- **Award type:** 3
- **Project period:** 2020-01-01 → 2021-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10012518

## Citation

> US National Institutes of Health, RePORTER application 10012518, UC Davis Alzheimer's Disease Core Center (3P30AG010129-29S2). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10012518. Licensed CC0.

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