# PDX Core

> **NIH NIH U54** · WISTAR INSTITUTE · 2020 · $313,602

## Abstract

Project Summary – PDX Core 
The PDX Core provides major resources to the program investigators, including melanoma PDX, melanoma 
cell lines and 3D models to explore new therapies. The melanoma PDX encompasses >450 different tumors 
representing all clinical and genetic groups of the disease. The primary focus of the PDX core is to establish 
new PDX and coordinate their characterization at the DNA, RNA, and protein levels. It then maintains the 
master cell bank, monitors for mouse pathogens, and collaborates with other investigators within the program, 
within the overall PDTC and outside scientists. The Core is also to central facilitator for exchanging PDX within 
the PDXNet for a coordinated effort on collaborations. The Core coordinates data storage and distribution to 
other investigators within the Program. 
The PDX Core is available to train investigators of the Program in all biological assays and models. Overall, 
this Core will provide efficient and high-quality service to all laboratories within this PDTC. 
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## Key facts

- **NIH application ID:** 10013148
- **Project number:** 5U54CA224070-03
- **Recipient organization:** WISTAR INSTITUTE
- **Principal Investigator:** Meenhard F Herlyn
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $313,602
- **Award type:** 5
- **Project period:** 2017-09-30 → 2022-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10013148

## Citation

> US National Institutes of Health, RePORTER application 10013148, PDX Core (5U54CA224070-03). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10013148. Licensed CC0.

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