# Genotyping/Virus Resource Core

> **NIH NIH P30** · YALE UNIVERSITY · 2020 · $202,626

## Abstract

Genotyping and Virus Production Core Module Abstract
The Genotyping and Virus Production Core Module will provide the means to incorporate modern molecular
and genetic techniques into the research programs of the entire vision research community at Yale. First, the
Module will supply genotyping and virus preparation assistance and services for laboratories working with
transgenic animals and/or viral techniques. Second, it provides and maintains a range of molecular biology
equipment to be shared among vision researchers and aids investigators by providing a service for those
without the facilities for basic or advanced molecular biology techniques. Third, it trains new investigators and
students in basic molecular biology techniques, including the use of viral vectors. Viral vectors are powerful
tools for gene delivery in terminally differentiated cells. For example, adeno-associated viruses (AAVs) have
enjoyed increasingly wide application in vision research for their many favorable features that include the lack
of pathogenicity, low immunogenicity, and the ability to maintain long-term transgene expression in neurons.
The Genotyping and Virus Production core module will be sufficient and well equipped to provide both virus
vector design and virus production to meet a variety of research needs among vision researchers at Yale.
Although many of the common viruses can be purchased from viral core facilities outside of Yale, having an in-
house capability for virus design and production will significantly enhance vision research by saving time and
cost and facilitating more efficient and innovative virus design with the convenience of in-person consultation
for specific research needs.

## Key facts

- **NIH application ID:** 10013207
- **Project number:** 5P30EY026878-05
- **Recipient organization:** YALE UNIVERSITY
- **Principal Investigator:** DAVID Paul ZENISEK
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $202,626
- **Award type:** 5
- **Project period:** 2016-09-01 → 2022-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10013207

## Citation

> US National Institutes of Health, RePORTER application 10013207, Genotyping/Virus Resource Core (5P30EY026878-05). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10013207. Licensed CC0.

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