# Core B: Liver Cell Isolation Core

> **NIH NIH P30** · UNIVERSITY OF KANSAS MEDICAL CENTER · 2020 · $282,650

## Abstract

PROJECT SUMMARY / ABSTRACT
The Liver Cell Isolation Core, formerly the Human Cell Isolation Core, is the only COBRE funded facility in the
U.S. dedicated to the isolation of liver cells from humans, mice and rats. The Liver Cell Isolation Core strives to
meet the following goals. 1) To provide isolated hepatocytes and specific non-parenchymal liver cells from
normal and diseased human and rodent livers for the support of scientific studies, grants and publications. 2)
To become a more comprehensive core by a collaborative affiliation with the University of Kansas Liver Center.
3) To establish a core lab that can operate without COBRE grant support through generation of its own
revenue and through other sources of institutional and/or NIH finding. The Core operates out of a state of the
art lab located on the campus of the University of Kansas Medical Center. The Core provides expert advice
regarding the isolation, culture and maintenance of hepatocytes and non-parenchymal cells. The Core is
under the direction of Dr. Hartmut Jaeschke and is staffed by a Core Technical Director, Mr. Kenneth Dorko,
and a Core Technician, Ms. Huina Cai. For COBRE Phase III, the Liver Cell Isolation Core will expand the
number of institutions from which it obtains liver specimens, increase the number of investigators that use its
resources and gradually increase its service fees. These actions, coupled with additional institutional and
future NIH support will allow the Core to become self-sustaining.

## Key facts

- **NIH application ID:** 10013240
- **Project number:** 5P30GM118247-05
- **Recipient organization:** UNIVERSITY OF KANSAS MEDICAL CENTER
- **Principal Investigator:** HARTMUT W. JAESCHKE
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $282,650
- **Award type:** 5
- **Project period:** 2016-08-15 → 2022-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10013240

## Citation

> US National Institutes of Health, RePORTER application 10013240, Core B: Liver Cell Isolation Core (5P30GM118247-05). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10013240. Licensed CC0.

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