# Longitudinal Effects of Extended Early Childhood Intervention

> **NIH NIH R01** · UNIVERSITY OF MINNESOTA · 2020 · $571,019

## Abstract

Summary
The project investigates links between participation in a large-scale established early childhood
intervention and well-being for the Chicago Longitudinal Study (CLS) cohort up to age 40 and for a new
generation cohort from the Midwest scale-up of the same program by age 12. The central purpose is to
determine if the effects of participation in the Child-Parent Center (CPC) Preschool-to-Grade 3 program
for different lengths of time are generalizable across time and context as well as impact long-run health
and well-being. New data will be collected on career success and a health interview will obtain key
physical and mental health diagnostics. Socio-emotional, mental health, and parent outcomes will be
assessed in the new cohort for direct application to current programs.
 Among the key questions are the following: (a) Is participation in the CPC program beginning in
preschool associated with better well-being in midlife for economic and career success, mental health, and
physical health? (b) Does participation in the scaled-up new generation program yield benefits on
cognitive, scholastic, and socio-emotional skills that are similar to the program evaluated in the CLS?,
and (c) Do the estimated effects of the new generation program vary by dosage, organizational attributes,
child/family demographics, and adverse childhood experiences? Economic benefits and costs as well as
generative mechanisms of change will be examined for translation to stakeholders.
 The study samples includes 1,404 program and matched comparison participants (Cohort 1) and a
new generation cohort of 2,314 participants from three geographically diverse districts implementing the
program beginning in 2012-13. They will be followed to age 12 while Cohort 1 will be tracked to age 40.
Extensive information is available from both cohorts but Cohort 2 is part of a scale up of CPC designed
for further expansion and sustainability. In the next five years, we will collect, obtain, and analyze a
comprehensive set of new data for physical health, psychological well-being, and career success (Cohort
1) and for socio-emotional, family, and education outcomes (Cohort 2). Continued collection of
administrative data of health, education, and earnings also will occur.
 The importance of assessing impacts on well-being is elevated by the current scale up of the CPC
program and for which knowledge of the generalizability of effects across generations is essential. Given
the large expansion of funding for preschool programs and evidence that the quality and continuity of
many programs are not sufficient to yield sustained gains, evidence on current programs are needed more
than ever. This is also consistent with the priority of Type 2 translational science.

## Key facts

- **NIH application ID:** 10013251
- **Project number:** 5R01HD034294-26
- **Recipient organization:** UNIVERSITY OF MINNESOTA
- **Principal Investigator:** ARTHUR J REYNOLDS
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $571,019
- **Award type:** 5
- **Project period:** 1995-09-01 → 2023-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10013251

## Citation

> US National Institutes of Health, RePORTER application 10013251, Longitudinal Effects of Extended Early Childhood Intervention (5R01HD034294-26). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10013251. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*