# I CARE for Vets: InCreasing Activity & REcovery for Veterans with PTSD

> **NIH VA I21** · MINNEAPOLIS VA  MEDICAL CENTER · 2020 · —

## Abstract

Veterans with posttraumatic stress disorder (PTSD) have poor physical functioning and there are no
existing interventions that effectively address this problem. Our long-term goal is to develop and implement
effective interventions to improve physical functioning and reduce risk for adverse health outcomes for Veterans
with PTSD. The overall objectives of the proposed project are to develop and pilot test a novel intervention
aimed at initiating and maintaining higher levels of physical activity for Veterans with PTSD. This new intervention
will address attitudinal and behavioral barriers to increasing physical activity for Veterans with PTSD. Particularly
relevant barriers for those with PTSD may include low perceived behavioral control for making positive long-
term lifestyle changes and personal attitudes about the harms (vs. benefits) of physical activity.
 The proposed work will meet two specific aims: 1) Adapt graded exercise therapy (GET) and
incorporate motivational interviewing and mobile health technology (mHealth) to increase physical activity for
Veterans with PTSD; and 2) conduct a pilot study to examine the feasibility and acceptability of the intervention
for a future randomized controlled trial. To achieve Aim 1, we will develop treatment manuals, training
procedures for interventionists, and processes for assessment of intervention fidelity. The intervention will use
GET to increase perceived behavioral control by enhancing knowledge about appropriate activities and helping
participants set appropriate and attainable daily goals for physical activity. We will also incorporate motivational
interviewing techniques and mHealth to enhance positive personal attitudes about physical activity. We will work
with our Veteran Engagement Panel for PTSD to refine topics and communication materials. In Aim 2, we will
enroll 3 groups of 6-8 participants (18-24 total) and use a concurrent mixed-methods approach to rapidly assess
feasibility and acceptability. Quantitative measures will include recruitment (proportion enrolled out of total
eligible); attendance (proportion who attend 75% of in-person visits); and retention (proportion who complete
post-intervention data collection). Qualitative assessment will consist of semi-structured interviews on
acceptability of intervention components (eg, format and topics of in-person visits, usability of mHealth), and
barriers and facilitators to attendance. At baseline, during, and post-intervention, we will also measure overall
and physical functioning, and collect data on other clinical variables (PTSD symptoms, depressive symptoms,
pain, fatigue, and sleep quality) to inform a future effectiveness trial.
 The proposed work is innovative because it is a novel combination of GET, motivational interviewing,
and mHealth to increase physical activity. It will also be the first intervention to focus on changing physical activity
as a means to improving physical functioning for individuals with PTSD. Succe...

## Key facts

- **NIH application ID:** 10013894
- **Project number:** 1I21RX003302-01A1
- **Recipient organization:** MINNEAPOLIS VA  MEDICAL CENTER
- **Principal Investigator:** Wei Duan-Porter
- **Activity code:** I21 (R01, R21, SBIR, etc.)
- **Funding institute:** VA
- **Fiscal year:** 2020
- **Award amount:** —
- **Award type:** 1
- **Project period:** 2020-06-01 → 2022-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10013894

## Citation

> US National Institutes of Health, RePORTER application 10013894, I CARE for Vets: InCreasing Activity & REcovery for Veterans with PTSD (1I21RX003302-01A1). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10013894. Licensed CC0.

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